![]() A fixed‐effect mode was applied and the outcome showed that patients receiving silicone gel had significantly lower scores than those in the control group (SMD = −0.55, 95% CI: −0.83 to −0.26, P =. 15 for pigmentation and height, respectively). In addition, we wanted to explore whether the form of dressings really mattered to treatment efficacy.įorest plot comparison of Vancouver Scar Scale scores between silicone gel and placebos or no treatment at 3 months after surgeryįor the comparison of pigmentation and height scores at 6‐ to 8‐month follow‐up, low heterogeneity was found among the studies ( I 2 = 0, P =. 7 We conducted a systematic review and meta‐analysis to see whether application of silicone gel in scars was effective. However, in a meta‐analysis by Hsu et al, topical silicone gel did not outperform placebos in pathological scar prevention, while silicone gel sheet once again showed efficacy. ![]() Topical silicone gel, another silicone‐based product for scar management, is also widely used in clinical practice. 5 According to the Cochrane meta‐analysis by O'Brien and Jones, silicone gel sheet as a way of pathological scar prevention was effective in high‐risk patients and improvement in scar thickness and scar colour was also reported in patients using silicone gel sheet for pathological scar treatment. 4 Silicone‐based products were deemed as the first‐line, gold standard therapy for scar management and have shown efficacy in both prevention and treatment of pathological scars. Silicone gel has been used in scar management since the 1980 seconds. 1, 2 Hypertrophic scars can develop from skin injuries caused by trauma, surgery, and burns, while keloids arise from skin wounds caused by trauma, shaving, surgery, and vaccination. Hypertrophic scars occurred in 16% patients with burns and the prevalence of keloids in Black Africans was reported to be around 3.5%. Pathological scars including hypertrophic scars and keloids are very common diseases. In summary, topical silicone gel was effective in post‐operative scar prevention. The performance of topical silicone gel and other non‐silicone topical treatment was also similar ( P > .05). As a result, topical silicone gel significantly reduced pigmentation, height, and pliability scores postoperatively compared with placebos or no treatment (Pigmentation: standard mean difference = −0.55, P =. The outcome data of Vancouver Scar Scale were extracted from the studies and their effect sizes were calculated using Review Manager 5.3. The systematic search was performed on PubMed, Web of Science and Embase, and six randomised controlled trials with a total of 375 patients were involved. To assess the efficacy of topical silicone gel in the management of scars, we conducted this meta‐analysis.
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